Applications of Whispering Gallery Mode Resonators for Biosensing

Optical Whispering Gallery Modes (WGMs) confined within dielectric microcavities are highly sensitive to perturbations in their surrounding medium. Due to the high quality (Q) of WGM resonances, it is possible to detect minute changes in the nominal wavelength of the resonance resulting in class of sensors with exquisite sensitivity. Even when immersed in aqueous solution, WGM sensors have the potential to be a true single molecule sensing method. This fact makes the WGM technique an ideal candidate for create biosensors for a wide variety of diagnostic applications. There are a growing number of examples in the literature exploring the use of WGM technologies for detecting biomolecules for a range of applications. This lecture will focus on current and future applications of WGM sensing for the detection and quantification of biomolecules in aqueous solutions.