Optical Methods for Quantifying Fluid and Solid Dynamics of Biological Systems

Many biological systems rely on a coupling between fluid flow and solid dynamics for proper functioning. One example is the flow-induced vibration of the human vocal folds that produces sound for speech and singing. In this case, developing an improved understanding of the fluid-solid interaction dynamics will lead to improved diagnosis, prevention, and treatment of voice disorders. In this presentation, optics-based measurement techniques for characterizing fluid flow and structural dynamics of biological systems, particularly the human vocal folds, are presented. Synthetic, self-oscillating, life-like models that simulate human vocal fold vibration are introduced. Examples of the use of state-of-the-art fluid and solid measurement techniques, including particle image velocimetry (PIV) and multi-view high-speed digital image correlation (DIC), are presented. Other recent advances in vocal fold modeling and measurement techniques are discussed.